Abstract
Placental alkaline phosphatase (PLAP) is a microvillar enzyme which plays a key role in the transport of human immunoglobulin G (IgG) across the human placenta. It has been used as a tumour marker in both ovarian and testicular malignancies.' A family of three different alkaline phosphatases is coded on chromosome 2.2 Intestinal alkaline phosphatase (lAP) exists in lower levels in serum of subjects of blood group A.3 Since PLAP is produced by the gene adjacent to lAP, I we have examined the possibility that PLAP in human serum is also related to ABO blood groups.
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