Abstract
Low S100ß Measurements via Jugular Venous Bulb Catheter During Pulsatile Perfusion in Coronary Bypass Grefting Operations
Highlights
Among peripheral tissues, brain is the most important organ and the most vulnerable one to ischemia during cardiopulmonary bypass (CBP), and it needs to be well protected [1]
In this study we aimed to determine whether the utilization of pulsatile or non-pulsatile cardiopulmonary bypass (CPB) makes a difference on the cerebral circulation by the measurements of biochemical serum markers and the jugular bulb oxygen saturation (SjVO2) in addition to near- infrared spectroscopy (NIRS)
Neurological complications that may develop after cardiac surgery are classified into two groups according to ACCAHA (American College of Cardiology and American Heart Asssosiation) classification [1-4]
Summary
Brain is the most important organ and the most vulnerable one to ischemia during cardiopulmonary bypass (CBP), and it needs to be well protected [1]. Neurological complications that may develop after cardiac surgery are especially due to embolization and hypoperfusion [2]. As a result of changes in cerebral blood flow during CPB, despite the cerebral autoregulatory system, it was found that there was a decrease in neurocognitive functions after pump up to 6 months [3]. Neurological complications that may develop after cardiac surgery are classified into two groups according to ACCAHA (American College of Cardiology and American Heart Asssosiation) classification [1-4]. While stroke-like events are called as type-1, neurocognitive complications are called type-2. Diagnostic methods are limited in the detection of type 2 complications. In order to detect neurological complications, serum markers such as S100ß, Neuron Specific Enolase (NSE) and adrenomedullin (ADM) were used [5-16]
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