Abstract

The information embodied in the entire nucleotide sequence of the bacteriophage λ genome was converted into a single three-dimensional space curve (H-curve) using a computer-graphics method. The front and side views of this highly compressed H curve display characteristis breakpoints that could be correlated on the DNA sequence to locations of special biological importance relevant to the transcription process. The utilization of low-resolution H-curves is proposed for the forthcoming task of analyzing and cataloging very long bacterial and eukaryotic DNA sequences.

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