Abstract
This study aimed to explore the therapeutic effects of neoadjuvant chemoradiotherapy (NCRT) on rectal cancer patients using the MRI based on low-rank matrix denoising algorithm, which was then compared with the postoperative pathological examination to evaluate its application value in tumor staging after NCRT treatment. 15 patients with rectal cancer who met the requirements of radiotherapy and chemotherapy after conventional MRI were selected as the research subjects. The conventional MRI images before and after NCRT treatment were divided in two groups. One group was not processed and set as the conventional group; the other group was processed with low-rank matrix denoising algorithm and set as the optimized group. The two groups of images were observed for the changes in the ADC value and length and thickness of the tumor before and after NCRT treatment. The two groups were compared with the pathological examination for the complete remission of pathology (pCR) after the NCRT treatment and the tumor stage results. The results showed that Root Mean Square Error (RMSE) and Peak Signal to Noise Ratio (PSNR) (18.9121 and 74.9911 dB) after introducing the low-rank matrix denoising algorithm were significantly better than those before (20.1234 and 70.1234 dB) (P < 0.05); there were notable differences in the tumor index data within the two groups before and after NCRT treatment (P < 0.05), indicating that the NCRT treatment was effective. The pathological examination results of pCR data of the two groups were not much different (P > 0.05); the examination results between the two groups were different, but no notable difference was noted (P < 0.05); in the optimized group, there was no notable difference between the MRI results and the pathological examination results (P < 0.05), while in the conventional group, there were notable differences in the MRI results and pathological examination results (P < 0.05). In conclusion, MRI images based on low-rank matrix denoising algorithm are clearer, which can improve the diagnosis rate of patients and better display the changes of the microenvironment after NCRT treatment. It also indicates that NCRT treatment has significant clinical effects in the treatment of rectal cancer patients, which is worth promoting.
Highlights
Nowadays, people’s living standards have been greatly improved resulting from the development of science and technology
According to the abovementioned result analysis, neoadjuvant chemoradiotherapy (NCRT) was effective in the preoperative down-stage treatment of rectal cancer. e conventional MRI can detect obvious changes in tumor morphology, while the pathological examination can detect the microenvironment changes inside the dead cells after NCRT. e image processed by the low-rank matrix denoising algorithm can restore the original information, displaying the morphological changes more clearly. e results showed that Root Mean Square Error (RMSE) and Peak Signal to Noise Ratio (PSNR) (18.9121 and 74.9911 dB) after introducing the low-rank matrix denoising algorithm were significantly better than those before (20.1234 and 70.1234 dB) (P < 0.05). ung et al [14] proposed that low-rank matrix denoising algorithm has a certain effect in processing MRI images. e results of this study were consistent with the conclusions of Valvano et al [15]
The MRI based on the low-rank matrix denoising algorithm was compared with conventional MRI and pathological examination to explore its application value in evaluating the therapeutic effects of NCRT for rectal cancer. e results showed that MRI images based on lowrank matrix denoising algorithm were clearer, which could improve the diagnosis rate of patients and better display the changes of microenvironment after NCRT treatment
Summary
People’s living standards have been greatly improved resulting from the development of science and technology. Food, housing, and transportation have seen changes of varying degrees, especially the food. People’s lack of self-control in diet leads to the digestive tract problems. Colorectal cancer has been a relatively common gastrointestinal tumor China in recent years, and its incidence is increasing year by year. Rectal cancer accounts for nearly 70%, with the patients being younger [1]. According to the data of the International
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