Abstract

Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Whole-genome sequencing and phylogenetic analysis show introduction of an H5N2 virus lineage from Mexico into poultry in the Dominican Republic, then divergence into 3 distinct genetic subgroups during 2007–2019.

Highlights

  • Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017

  • The virus reassorted with the local avian influenza (H6N1) virus strain that has been enzootic in chickens in Taiwan since 1997 to produce reassortant H5N2 virus possessing hemagglutinin (HA) and neuraminidase (NA) genes of H5N2 virus from Mexico and internal genes of the Taiwan H6N1 virus

  • In 2007, outbreaks of Low pathogenicity avian influenza virus (LPAIV) H5N2 occurred among chickens in Santo Domingo and Higüey-La Otra Banda, Dominican Republic, and were reported to the World Organisation for Animal Health (OIE) [6]

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Summary

Introduction

Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Low pathogenicity avian influenza virus (LPAIV) subtype H5N2 has caused outbreaks in poultry in Mexico since 1993 and mutated into highly pathogenic avian influenza virus (HPAIV) H5N2 during 1994–1995 [1]. The reassortant H5N2 virus mutated into an HPAIV and caused outbreaks in poultry in Taiwan during 2012 [5].

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