Low nM Detection Limits at Porous 1-3 nm Thick Membrane-Coated Nanostructured Microdisk Electrodes

Abstract

Low (15 nM) limits of detection (LOD) of dopamine were obtained at porous 1–3 nm-thick overoxidized polypyrrole (OPPY) membrane-coated microdisk carbon fiber electrodes of small size (r=3.5 µm). The excellent mass transport through the porous OPPY membrane (efficiency as good as solution transport) contributes to the low LOD, together with dopamine preconcentration in the membrane. Structural characterization of the membrane coated electrodes confirms the contribution of membrane nanostructure to the high sensitivity and the low LOD.