Abstract
Very few therapeutic options exist for patients who survive severe brain injury but fail to fully recover and develop a disorder of consciousness (e.g. vegetative state, minimally conscious state). Low Intensity Focused Ultrasound (LIFU) employs low-energy sound waves to allow noninvasive, transient, and well tolerated excitatory or inhibitory stimulation of central regions of the brain (here, the thalamus). We here present preliminary data on its use as a neurostimulatory intervention in acute DOC patients.
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