Abstract

The coupling of innovative technologies has emerged as a smart alternative for the process intensification of bioactive compound extraction from plant matrices. In this regard, the development of hybridized techniques based on the low-frequency and high-power ultrasound and high-pressure technologies, such as supercritical fluid extraction, pressurized liquids extraction, and gas-expanded liquids extraction, can enhance the recovery yields of phytochemicals due to their different action mechanisms. Therefore, this paper reviewed and discussed the current scenario in this field where ultrasound-related technologies are coupled with high-pressure techniques. The main findings, gaps, challenges, advances in knowledge, innovations, and future perspectives were highlighted.

Highlights

  • The development of innovative processes based on low-frequency and high-power ultrasound technology has grown in the last two decades due to its large versatility and application in several industrial sectors

  • Regarding the ultrasound-assisted extraction processes, the ultrasound performance as a process improver is associated with its action mechanism, whose principle is the acoustic cavitation phenomenon

  • Low-frequency ultrasound technology can be coupled with high-pressure extraction processes in different ways, namely: the raw material can be pretreated in ultrasound equipment separately from the high-pressure extraction equipment; it can be ultrasonically pretreated inside the extractor by coupling the ultrasound to the extraction vessel; and for equipment that has ultrasound coupled with the extraction vessel, sonication can occur in pulses or while the high-pressure extraction process lasts

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Summary

Introduction

The development of innovative processes based on low-frequency and high-power ultrasound technology has grown in the last two decades due to its large versatility and application in several industrial sectors. The use of low-frequency ultrasound has been widely studied as a means of intensifying the extraction process while preserving the functionality and biological activity of plant extracts [13] In this regard, the coupling of low-frequency ultrasound to other clean emerging technologies to get synergetic effects is an interesting strategy for recovering bioactive compounds from plant matrices. The authors’ experience was inserted in this revision to give a particular viewpoint and future outlooks in this promising area. This is certainly not the first review that evaluates and extolls the virtues of ultrasound-based extraction of target compounds from renewable biomasses. It makes a relevant contribution to food-related and chemical-related areas on the challenges and future perspectives of using ultrasound technology coupled with high-pressure technologies

Fundamentals and Mechanisms
Low-Frequency Ultrasound Technology
High-Pressure Technologies
Low-Frequency Ultrasound Coupled with High-Pressure Technologies
Low-Frequency Ultrasound Coupled with SFE
Low-Frequency Ultrasound Coupled with PLE
Innovative Processes for the Extraction of Phytochemical Compounds
Low-Frequency Ultrasound as a Single Operation
Low-Frequency Ultrasound in the Industrial Scale
Findings
Challenges and Future Perspectives
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