Abstract
26 patients with chronic urinary tract infections (UTI) were treated with 1 tablet of 100 mg trimethoprim (TMP) once daily for up to 6 months as long term prophylaxis. The recurrence rate before prophylaxis was 26/100 months, compared to a significantly lower frequency (3.3 recurrences/100 months, p less than 0.001) during prophylaxis. The post-prophylactic rate returned to the pre-prophylaxis rate: 23 recurrences/100 months. All Escherichia coli strains causing post-prophylactic UTI were TMP sensitive. The number of rectal enterobacteria were markedly reduced during prophylaxis (p less than 0.05). A 10% recovery of TMP resistant enterobacteria from rectal swabs was noted early (less than or equal to 1 month) during prophylaxis, but no significant further accumulation occurred.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.