Abstract

RATIONALE: Interstitial lung disease (ILD) is one of the major organ involvements associated with dermatomyositis and polymyositis (DM/PM), and it often affects the patient's survival. Glucocorticoid alone has been shown to be insufficient even as an initial treatment for this manifestation, especially when anti-aminoacyl tRNA synthetase antibodies are present. We examined the efficacy of a lower dose of tacrolimus and the usefulness of KL-6 as a disease surrogate marker.

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