Abstract
AbstractBackground:The Coronavirus disease 2019 (COVID-19) is spreading rapidly throughout the world. Lung is the primary organ which the COVID-19 virus affects and leads to pneumonia, an acute respiratory distress syndrome. COVID-19 infects the lower respiratory system, and the lung’s response to this infection is recruiting macrophages and monocytes leading to inflammation, this response causes widespread damage to the lung’s airways.Aim:The purpose of this study is to review studies of using low-dose radiation as a treatment for the inflammation of the tissue and pneumonia resulting from COVID-19. These studies were compared with the risk of developing lung cancer during performed dose for the treatment of COVID-19 in radiation therapy.Materials and methods:Our study focused on in vitro, in vivo and clinical reports of using low-dose radiation for the treatment of inflammation, pneumonia and COVID-19. The risk of lung cancer resulting from suggested dose in these studies was also evaluated.Conclusion:From the review of articles, we have found that low-dose radiation can lead to improvement in inflammation in different line cells and animals; in addition, it has been effective in treating inflammation and pneumonia caused by COVID-19 in human up to 80%. Since suggested doses do not remarkably increase the lung cancer risk, low-dose radiation can be an adjuvant treatment for COVID-19 patients.
Highlights
The Coronavirus disease 2019 (COVID-19) is spreading rapidly throughout the world
Based on the present study, using BEIR VII model to estimate the risk of lung cancer at 0.5 Gy for patients with coronavirus disease aged 25, 45, 65 years and treated by low-dose radiation, the incidence of lung cancer can increase by 2.1%, 2.09% and 1.68%, respectively, for men, or almost three times for women
A review of in vitro and in vivo studies showed that the use of low doses up to 1.5 Gy eliminates tissue inflammation and pneumonia by stimulating macrophages
Summary
Cite this article: Ghaznavi H, Elahimanesh F, Abdolmohammadi J, Mirzaie M, and Ghaderi S. (2021) Low-dose radiation therapy: a treatment for pneumonia resulting from COVID-19. Cite this article: Ghaznavi H, Elahimanesh F, Abdolmohammadi J, Mirzaie M, and Ghaderi S. (2021) Low-dose radiation therapy: a treatment for pneumonia resulting from COVID-19. Journal of Radiotherapy in Practice page 1 of 4.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
