Abstract

THE CONVENTIONAL TREATMENT for International Society of Heart and Lung Transplantation (ISHLT) grade 3A acute cardiac allograft rejection (AR) is intravenous steroid therapy. To reduce the total steroid dose and utilize an outpatient environment, low-dose oral prednisone protocols have been developed for AR treatment when the patient does not display significant hemodynamic compromise. This option was not only effective but also associated with fewer side effects and with reduced cost. The aim of the present study was to analyze the results of an outpatient low-dose oral prednisone protocol in AR without hemodynamic compromise.

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