Low-dose colchicine after MI reduced a composite ischemic cardiovascular outcome vs placebo.

Abstract

ACP Journal Club21 April 2020Low-dose colchicine after MI reduced a composite ischemic cardiovascular outcome vs placeboRichard G. Bach, MDRichard G. Bach, MDWashington University School of Medicine, St. Louis, Missouri, USA (R.G.B.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJ202004210-039 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationTardif JC, Kouz S, Waters DD, et al. Efficacy and safety of low-dose colchicine after myocardial infarction. N Engl J Med. 2019;381:2497-2505. https://pubmed.ncbi.nlm.nih.gov/31733140Clinical Impact RatingsGIM/FP/GP: Cardiology: References1 Cannon CP, Blazing MA, Giugliano RP, et al. Ezetimibe added to statin therapy after acute coronary syndromes. N Engl J Med. 2015;372:2387-97. [PMID: 26039521] Google Scholar2 Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL. Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol. 2013;61:404-10. [PMID: 23265346] Google Scholar3 Deftereos S, Giannopoulos G, Angelidis C, et al. Anti-Inflammatory treatment with colchicine in acute myocardial infarction: a pilot study. Circulation. 2015;132:1395-403. [PMID: 26265659] Google Scholar4 Vaidya K, Arnott C, Martínez GJ, et al. Colchicine therapy and plaque stabilization in patients with acute coronary syndrome: a CT coronary angiography study. JACC Cardiovasc Imaging. 2018;11:305-16. [PMID: 29055633] Google Scholar5 Verma S, Eikelboom JW, Nidorf SM, et al. Colchicine in cardiac disease: a systematic review and meta-analysis of randomized controlled trials. BMC Cardiovasc Disord. 2015;15:96. [PMID: 26318871] Google Scholar Author, Article, and Disclosure InformationAffiliations: Washington University School of Medicine, St. Louis, Missouri, USA (R.G.B.)Disclosures: The commentator has disclosed no conflicts of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M19-3041.This article was published at Annals.org on 7 April 2020. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 21 April 2020Volume 172, Issue 8Page: JC39KeywordsAcute coronary syndromeAnginaColchicineCoronary arteriesCoronary revascularizationHospitalizationsMyocardial infarctionStable coronary artery diseaseStrokeTreatment guidelines ePublished: 21 April 2020 Issue Published: 21 April 2020 Copyright & PermissionsCopyright © 2020 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...