Abstract
Case Report We present a 42-year-old male affected with biopsy-proven vulgar psoriasis admitted to our Department for the appearance of an erythrodermic psoriasis (Fig. 1A). Before admission to the hospital patient suffered from relapsing episodes of diffuse psoriasis, since the age of 19, which responded well to topical emollients and UVB therapy. 5 years ago has suffered from hepatitis C. The laboratory tests did not revealed any abnormalities related to renal and hepatic function. The patient was treated with ciclosporin 2.5 mg/kg per day, doxycycline (2 x 100mg per day) and hydroxyzine tablets for symptomatic relief. The clinical response was not immediate, although at the begining of the third week of the therapy a marked reduction of erythema and scaling was evident. Since week 4 of the treatment, ciclosporin was gradually reduced (0.5 mg/kg per day). Presently patient receives 1.17 mg/kg per day and is under a complete remission (Fig. 1B). LOW-DOSE CICLOSPORIN THERAPY OF ERYTHRODERMIC PSORIASIS
Highlights
Psoriasis is a chronic, recurrent inflammatory skin disease which affects around 2% of the population and is characterized by erythematous and scaly macules and papules of greatly varying degree of involvement
Ciclosporin (Cs) is a therapeutic agent rarely used in the treatment of erythrodermic psoriasis as a monotherapy [1]
Case Report We present a 42-year-old male affected with biopsy-proven vulgar psoriasis admitted to our Department for the appearance of an erythrodermic psoriasis (Fig. 1A)
Summary
Recurrent inflammatory skin disease which affects around 2% of the population and is characterized by erythematous and scaly macules and papules of greatly varying degree of involvement. 133, 04-008 Warsaw, Poland 7Department of Dermatology, Military Institute of Health, Szaserów 128 Str., 00-909 Warszawa, Poland 8School of Economics, Law and Medical Sciences in Kielce, Jagiellońska 109A Str., 25-734 Kielce, Poland Corresponding author: Dr Ryszard Galus, MD PhD Cite this article: Galus R, Borowska K, Jędrych M, Jodłowska-Jędrych B, Niemczyk L, Antiszko M, Terlikowska-Brzósko A, Owczarek W, Zabielski Z.
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