Low-dose aspirin in prevention of toxaemia of pregnancy. Does it have a place?

Abstract

Clinical investigations indicate that in women thought to be at increased risk of developing toxaemia of pregnancy, effective prevention of toxaemia of pregnancy can be achieved by the use of low-dose aspirin. Early clinical impressions are that in women with pre-existing hypertension, the blood pressure elevation is also rendered more easily manageable by inclusion of low-dose aspirin in their treatment regimen. In women with pre-existing hypertension and autoimmune disease — situations that carry a particularly unfavourable prognosis for the fetus — the development of superimposed toxaemia of pregnancy can be effectively prevented by daily administration of low-dose aspirin (60 to 100 mg/day).