Abstract
The objective of this cross‐sectional study was to evaluate the impact of diet on homocysteine (Hcy), vitamin B12 and folate status in women living in Queretaro (central Mexico). Average mean values for age, weight, height and BMI were 37.6±10.3 ys, 68.4 ± 14.6 kg, and 151.6±5.2 cm and 29.8±6.0 kg/m2, respectively. Mean concentrations of serum vitamin B12, folate and Hcy were 331.5±209.9 pmol/L, 21.1±8.2 nmol/L and 10.9±3.2 nmol/L. Vitamin B12 deficiency was observed in 11.4% of the participants. In addition 21.2% presented marginal status. Only 5.4% of the women were folate deficient. Prevalence of hyperhomocysteinemia was 32.6%. B12 deficient women had inadequate intakes of vitamin B12 in about 50% (<EAR). Increase in Hcy was related to dietary intake and serum concentrations of vitamin B12. Being vitamin B12 deficient increase 2.8 times the risk of presenting hyperhomocysteinemia. Dietary folate was no related to Hcy, but serum values were. Vitamin B12 deficiency as a result of low dietary intake was the most important factor associated to high Hcy in blood in these Mexican women.
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