Abstract
The number of the indirect methods for LDL-C estimation is growing. Our result support the reliability of new Anandaraja's formula for low-density lipoprotein estimation from total cholesterol and triglycerides.
Highlights
Our team recently compared two methods of estimation of low-density lipoprotein cholesterol, the direct Wako method versus Friedewald's formula [4]
We studied over 10 000 consecutive patients with different diseases, from mixed rural and urban Brazil population
In each very low-density lipoprotein particle secreted from the liver, and in each intermediate-density lipoprotein, low-density lipoprotein and lipoprotein (a) particles, a single molecule of apolipoprotein B is present from the time of its assembly to its catabolism, which does not exchange between lipoproteins
Summary
Our team recently compared two methods of estimation of low-density lipoprotein cholesterol, the direct Wako method versus Friedewald's formula [4]. Anandaraja et al [3] published new formula for LDL-C estimation from two other parameters, total cholesterol and triglycerides, as substitution to well known Friedewald's formula. We studied over 10 000 consecutive patients with different diseases, from mixed rural and urban Brazil population. Better correlation in both total population (r = 0,969) and patients with triglyceride
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