Abstract

Viral infections are a significant cause of morbidity after allogeneic stem cell transplantation. Modifying intensity of immunosuppression according to immune function may reduce infections. Currently, no routine functional assays to monitor immune function of the new graft exist. The Cylex ImmuKnow assay is a FDA approved test that quantifies cellular immune function by measuring intracellular ATP activity released by PHA-stimulated CD4T cells in blood, and has correlated with solid organ graft outcomes.

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