Abstract
Introduction: Loss of vertical gaze in combination with oculomotoric disturbances are called Parinaud-syndrome. The variable loss of vertical gaze is caused by unilateral tegmental lesions in the mesencephalon. Upward eye movement cause convergence reactions and nystagmus. The often large pupils react slowly to light and pathological eyelid-retraction may occur. Tumours, multiple sclerosis or disrupted blood supply are mainly responsible for the Parinaud syndrome.
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