Los efectos cardiopulmonares del Cough Assist® son similares a los promovidos por la tos voluntaria en sujetos sanos. Ensayo clínico aleatorizado

Abstract

ObjectiveTo analyse the haemodynamic and ventilatory effects of the application of Cough Assist® and compare them to those caused by the realization of voluntary cough. Material and methodsA randomised clinical trial. The sample consisted of 24 young healthy subjects who underwent three different protocols using Cough Assist® with common respiratory pressures into clinical practice: 30S – pressure I/E +30/–30 cmH2O; 50S – pressure I/E +50/– 50 cmH2O; and voluntary cough. Protocols apply to all subjects, with a time interval between them of at least 24hours. The parameters evaluated were heart rate, blood pressure, peripheral oxygen saturation, slow vital capacity and peak expiratory flow prior to application protocols (PRE), immediately after (POST) and 20minutes after (20’ POST). Statistical analysis was performed by ANOVA of i or ii pathways and post hoc of Bonferroni. For all analysis were considered a level of statistical significance of P<.05. ResultsThe effects caused by the Cough Assist® were similar to those of voluntary coughing. In women, none of them cause significant impact on the evaluated parameters; in men, both machine and voluntary cough led to increased heart rate, and the application of the Cough Assist® increased peripheral oxygen saturation. The other variables remained unchanged. ConclusionThe application of the Cough Assist® in medium and high pressure does not cause relevant cardiorespiratory repercussions, being similar to the physiological effects caused by the voluntary cough.