Abstract
Oral lorcaserin (Belviq®), a novel selective serotonin 5-HT2C receptor agonist, is indicated in the USA as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management of obese adults, or overweight adults with at least one weight-related co-morbidity. In 12-month clinical studies, lorcaserin was more effective than placebo in reducing weight in obese or overweight adults with or without type 2 diabetes mellitus. It is well tolerated and does not appear to be associated with an increased risk of valvulopathy.
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