Abstract
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood. The original diagnostic criteria were introduced in 1989. However, published studies show large heterogeneity in PFAPA patients, promting attempts at refining the criteria.
Highlights
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood
Children diagnosed with PFAPA were prospectively recruited from a large
Diagnosis was made by pediatric rheumatologists
Summary
Aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood. The original diagnostic criteria were introduced in 1989. Published studies show large heterogeneity in PFAPA patients, promting attempts at refining the criteria
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