Abstract
The SPRINT trial’s serious problems in internal and external validity require great caution in implementing the new US blood pressure guideline.
Highlights
The recently proposed revision of the Eighth Joint National Committee (JNC-8) guideline on hypertension supported by the American Heart Association (AHA), and the American College of Cardiology (ACC) [1], recommends a target systolic blood pressure (SBP) of 130 mm Hg or lower for all hypertensive individuals
The recommendations of the guideline were heavily influenced by the results of the SPRINT trial [2], which compared a standard treatment group with a target SBP
Even though the American College of Physicians (ACP) / Association of Family Physicians (AAFP) blood pressure guideline has itself been criticised for lacking author expertise [6], this cannot be taken too seriously, as primary care physicians are probably best equipped and positioned as generalists to make an overall clinical judgment on the management of hypertension in older adults and to practice the “first, do no harm” principle
Summary
The following full text is a publisher's version. For additional information about this publication click this link. Please be advised that this information was generated on 2022-03-01 and may be subject to change. Correspondence: Marcel GM Olde Rikkert, MD MSc, Dept Geriatrics, 925 Radboudumc, Postbox 9101, NL-6500 HB, Nijmegen, Marcel.OldeRikkert[at]Radboudumc.nl
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