Abstract

The reproducibility of the intravenous fat tolerance test (IVFTT) with Intralipid was studied in 26 healthy volunteers, in whom the test was repeated after 5-9.5 years (mean interval 6.5 years). Mean body mass, IVFTT fractional removal rate and serum TG (triglyceride) concentration were not significantly changed with time, whereas a slight increase of the serum cholesterol concentration from 5.09 +/- 0.12 to 5.54 +/- 0.19 mmol/1 (P less than 0.05) was found. The coefficient of variation intra-individually for the IVFTT k2 value was 16%. The corresponding figure for the serum TG concentration was 29%. The results suggest that the IVFTT might be a useful tool in long-term evaluation of serum TG abnormalities.

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