Abstract
Weber–Christian disease is a rare form of lobular panniculitis characterized by painful subcutaneous nodules on the trunk and limbs commonly concurrent with systemic manifestations and a tendency to relapse. Known are only sporadic cases of a long-term (more than 5-year) followup of patients with Weber–Christian disease. For this reason, there are neither prognostic criteria for the disease no proven conventional treatment option now. The paper describes a clinical case of a female patient with a verified diagnosis of Weber–Christian disease who has a sustained subclinical remission due to low-dose prednisone use and basic antirecurrent therapy.
Highlights
Weber–Christian disease is a rare form of lobular panniculitis characterized by painful subcutaneous nodules on the trunk and limbs commonly concurrent with systemic manifestations and a tendency to relapse
The paper describes a clinical case of a female patient with a verified diagnosis of Weber–Christian disease who has a sustained subclinical remission due to low-dose prednisone use and basic antirecurrent therapy
Nanke Y, Ishiguro N, Yago T, et al A case of Weber-Christian disease with later development of rheumatoid arthritis
Summary
Weber–Christian disease is a rare form of lobular panniculitis characterized by painful subcutaneous nodules on the trunk and limbs commonly concurrent with systemic manifestations and a tendency to relapse. Болезнь Вебера–Крисчена – редкая форма лобулярного панникулита, характеризующаяся развитием болезненных подкожных узлов на туловище и конечностях часто в сочетании с системными проявлениями и тенденцией к рецидивам. Известны единичные случаи длительного (более 5 лет) наблюдения пациентов с болезнью Вебера–Крисчена. По этой причине в настоящее время не существует прогностических критериев заболевания и доказанного общепринятого метода лечения.
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