Long-term curative effect of balloon dilatation combined with triamcinolone acetonide through fiberoptic bronchoscopy on tracheobronchial stenosis

Abstract

Objective To analyze the long-term curative effect of balloon dilatation combined with triamcinolone acetonide through fiberoptic bronchoscopy on tracheobronchial stenosis and its effect on forced expiratory volume in one second (FEV1) and fasting blood glucose. Medthods Twenty patients with benign airway stenosis in the North Ares of the First People’s Hospital Affiliated to Shanghai Jiao Tong University from January 2017 to December 2017 were randomly divided into control group and treatment group, with 10 cases in each group. The control group was treated with balloon dilatation guided by bronchoscopy. The treatment group was treated with balloon dilatation guided by bronchoscopy and local injection of triamcinolone acetonide. Airway stenosis and improvement in shortness of breath were observed in both groups half a month and six months after treatment. To evaluate the long-term efficacy of balloon dilatation combined with triamcinolone acetonide local injection under bronchoscopy and its effect on FEV1 and blood glucose were evaluated. Results Each of the 20 patients underwent high-pressure balloon dilatation 2-4 times, with an average of 3 times. Half a month after treatment, there was no significant difference in airway stenosis, dyspnea improvement or FEV1 between the control group and the treatment group (P>0.05). However, 6 months after treatment, the incidence of restenosis in the control group was higher than that in the treatment group(P 0.05). Conclusions Balloon dilatation combined with triamcinolone acetonide has obvious curative effect on tracheobronchial stenosis, of which the long-term effect is remarkable. It can reduce the number of balloon dilatation, effectively improve the tracheobronchial stenosis and safety, so it is recommended to be widely used in clinical. Key words: Balloon dilatation; Triamcinolone acetonide; Benign tracheobronchial stenosis