Long-term clinical outcome and prognosis after treatment of the first generation drug-eluting stent thrombosis

Abstract

There are many reports concerning about the incidence, predictor, and the in-hospital outcomes of stent thrombosis (ST) of drug-eluting stent (DES) [ 1 Jeremias A. Sylvia B. Bridges J. et al. Stent thrombosis after successful sirolimus-eluting stent implantation. Circulation. 2004; 109: 1930-1932 Crossref PubMed Scopus (326) Google Scholar , 2 Airoldi F. Colombo A. Morici N. et al. Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment. Circulation. 2007; 116: 745-754 Crossref PubMed Scopus (422) Google Scholar , 3 Kuchulakanti P.K. Chu W.W. Torguson R. et al. Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents. Circulation. 2006; 113: 1108-1113 Crossref PubMed Scopus (621) Google Scholar , 4 Win H.K. Caldera A.E. Maresh K. et al. Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. JAMA. 2007; 297: 2001-2009 Crossref PubMed Scopus (315) Google Scholar , 5 Ong A.T. Hoye A. Aoki J. et al. Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation. J Am Coll Cardiol. 2005; 45: 947-953 Abstract Full Text Full Text PDF PubMed Scopus (456) Google Scholar , 6 Iakovou I. Schmidt T. Bonizzoni E. et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005; 293: 2126-2130 Crossref PubMed Scopus (2930) Google Scholar ]. However, there are limited data for the long-term outcomes of patients who have been treated for ST after DES implantation and recurrence rate of ST in real world. The purpose of the present study was to investigate the recurrence rate and the long-term outcomes of patients who successfully treated for first generation DES thrombosis.