Abstract
Osteoporosis is known to occur in association with inflammatory bowel disease (Compston et al., 1987) and recently we demonstrated rapid rates of spinal trabecular bone loss in these patients (Motley et al., 1988). The pathogenesis of bone loss is likely to be multifactorial, with corticosteroid therapy, ovarian deficiency, malabsorption and malnutrition all playing a role. However, at present we do not know whether bone loss in these patients is generalised or occurs only at certain sites. In this study we measured longitudinal changes in total body calcium in a group of patients with inflammatory bowel disease and compared these with changes in spinal trabecular bone mineral density and radial cortical bone mineral content.KeywordsInflammatory Bowel DiseaseBone LossBone Mineral ContentSingle Photon AbsorptiometryTotal Body CalciumThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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