Longitudinal, radial and circumferential 2-dimensional strain for quantitative analysis of regional left ventricular systolic dysfunction in patients with coronary artery disease

Abstract

Objective To assess longitudinal, radial and circumferential systolic strain of regional myocardium in patients with coronary artery disease by 2-dimensional strain echocardiography, and to explore stenosis of coronary artery impacting on regional left ventricular systolic dysfunction in quietscent condition. Methods Twenty-six patients with coronary artery disease were entrolled into this study and 26 healthy volenteers in the control group. The two-dimensional loop-einec were obtained in apical 4-chamber view,apical 2-chamber view and long axis view of left venricular, and three levels of the short axis views (mitral valve,papillary muscle and cardiac apex). According to left ventricle 18 segments divla, there were 194 affected myocardiums in 26 cases. According to stenosis degrees of coronary artery, the affected myocardiums were divided into two groups: group A (coronary stenosis degree≤70%) and group B (coronary stenosis degree>70%). Longitudinal, radial and circumferential systolic strain (SL, SR, SC) from regional myocardium were analyzed. Results Group A had 90 segments. Compared with control group,SL was decreased significantly from control group (P 0.05). Group B had 104 segments. Compared with control group, SL, SC and SR were decreased significantly in group B(P <0.05). There were significant differences in SL,SC and SR between group A and group B(P<0.05). Conclusions Systolic dysfunction of left ventrieular regional myocardium in patients with coronary artery disease could be accuratly analyzed by 2-dimensional strain echocardiography. Changes of SL,SC and SR of regional myoeardium could reflect coronary stenosis severity degree. Key words: Echoardiography; Coronary disease; Ventricular function, left; Two-dimensional strain