Longitudinal Followup of Incidentally Detected Pseudotumors in Patients with Metal on Metal Implants: A Retrospective Study.

Abstract

Background:This study describes the significance and temporal evolution of incidentally detected, presumed, metal-induced reactive periprosthetic masses in patients with metal on metal (MoM) hip arthroplasty and its management. The literature concerning the temporal evolution of these lesions is meagre and so it is still unclear, whether asymptomatic patients with periprosthetic collections should undergo revision.Materials and Methods:Patients with MoM hip replacements fitted with a recalled implant (ASR, DuPuy) often undergo magnetic resonance imaging with metal artifact reduction sequences to look for complications. From a cohort of 136 asymptomatic patients, with 181 MoM hips, hips with a mention of periprosthetic masses in their reports at first presentation, and a repeat scan within 6 months to 3 years were selected for this retrospective study. Patients with complications such as loosening, osteomyelitis, and muscle/tendon tears were excluded from the study, and the final study cohort consisted of 55 MoM hips and 61 periprosthetic masses. Ethics committee approval is not required in our institution for retrospective studies. The followup scans of each patient were compared, and the periprosthetic masses were described to have progressed, regressed, or remained unchanged.Results:Comparison revealed that 29 of the 61 reactive masses remained unchanged, 20 regressed, while only 12 showed progression. The study, therefore, has maximum power as the outcome of interest, i.e., regression or unchanged status of the pseudotumors, was seen in approximately 80% (more than half) of the study group. The P value of the study was < 0.005.Conclusion:Periprosthetic soft tissue masses are not uncommon in patients with MoM hips. The majority of them in asymptomatic individuals remain stable or regress in the short to medium term, and close followup or decisions on revision surgery may not be warranted in asymptomatic patients.