Longitudinal Associations of Social Support and Gait Speed Decline

Abstract

AbstractBackgroundSocial support predicts functional and cognitive decline and is associated with brain regions that are important for both cognitive, and motor functions. Gait speed declines years before dementia onset, but the associations between social support and gait speed decline in aging is not well understood. This study examined longitudinal associations between social support and gait speed in older adults without dementia.MethodSocial support and gait data from 592 older adults without dementia (Mdn age 75 years, IQR 71,80, 55.3% female, 79.1% Caucasian) enrolled in the Central Control of Mobility in Aging (CCMA) study was examined. Overall support, emotional support, tangible support, affectional support, and positive social interactions, from the Medical Outcomes Study Social Support Survey at baseline were the predictors of interest. Annual change in simple (walking at normal pace) and complex (walking while reciting alternate letters of the alphabet) gait speed (cm/s) were the primary outcomes. Linear mixed effects models were used to examine the associations between change in single and complex gait speed and baseline social support, adjusting for gender, race, depression, overall cognition, comorbidities, and marital status.ResultThe mean annual change in gait speed was 1.9 cm/s during the simple walking condition and 1.07 cm/s during the complex walking condition. Tangible support was the only social support measure that predicted decline in simple and complex gait speed over a median follow up of 3 years. The annual decline in gait speed was 0.52 cm/s (p = 0.008, CI ‐0.91, ‐0.13) and 0.51 cm/s (p = 0.02, CI ‐0.95, ‐0.07) greater among those with low tangible support than among those with high tangible support during simple and complex walking conditions, respectively.ConclusionTangible support is a potentially modifiable risk factor for gait speed decline Further study is needed to examine the mechanisms behind the observed associations and potentials for intervention.This research was supported by NIH/National Center for Advancing Translational Science (NCATS) Einstein‐Montefiore CTSA Grant Number KL2 TR002558