Longer Pain to Balloon Times and Trend for More Deaths Among Diabetics Undergoing PPCI

Abstract

Objectives: To assess outcome differences by gender in our primary PCI population. Methods:We retrospectively analysed the PCI database at TheCanberraHospital for patients undergoing primary PCI between 2008 and 2012. Mean follow up by letter, phone and review of hospital records was 331 days. Results: Of 714 patients, 158 (22%)were women. Mean age was 68.7 compared with 59.5 for men (p< 0.0001). Men were more likely to be smokers (p= 0.02) and to have had previous PCI and CABG (p= 0.02), whereas there was a trend formorewomen to have diabetes (p= 0.1).Other risk factors and incidence of cardiogenic shock were similar. No of vessels diseased, no of stents and rate of successful PCI (98%) was the same for both genders. Median pain to hospital (134.5min vs 114.5min, p< 0.0001) and pain to balloon times (192.5min vs 173.5min, p 0.0017) were significantly longer inwomen butmedian hospital to balloon time was similar (54.5min vs 51min, p 0.43). Incidence of stroke and major adverse cardiovascular events was significantly higher in women but incidence of death was not statistically different. Stent thrombosis was more likely in men. Conclusions:WomenundergoingPPCI forSTEMI in the ACT are older, with longer pain to balloon times and a significantly higher risk for CVA and overall MACE.