Abstract
One of the methods of therapy for atopic dermatitis is long-wavelength ultraviolet therapy A (UVA-1- therapy). This review aims to provide the mechanisms of action of UVA-1-therapy an overview about the effectiveness of UVA-1-therapy in patients with atopic dermatitis taking into account factors that can affect the effectiveness of treatment radiation dose, skin phototype of patients, concomitant drug therapy. The available data on a decrease in the severity of atopic dermatitis as a result of the course of UVA-1-therapy and on a decrease in the severity of itching in patients are presented. The data on the rate of onset of the therapeutic effect of UVA-1-therapy and the duration of its maintenance are considered. The safety of UVA-1-therapy is discussed, and the most frequent undesirable effects a feeling of warmth, fever, itching, hyperpigmentation, are given. The possibility of developing side effects requiring discontinuation of treatment is assessed. The data obtained indicate the effectiveness and safety of the UFA-1-radiation in the treatment of patients with moderate-to-severe atopic dermatitis.
Highlights
One of the methods of therapy for atopic dermatitis is long-wavelength ultraviolet therapy A (UVA-1therapy)
This review aims to provide the mechanisms of action of UVA-1-therapy an overview about the effectiveness of UVA-1-therapy in patients with atopic dermatitis taking into account factors that can affect the effectiveness of treatment — radiation dose, skin phototype of patients, concomitant drug therapy
Чтобы получить возможность сопоставлять эффективность УФА-1-терапии с эффективностью других методов лечения больных атопическим дерматитом, необходима оценка таких широко используемых в настоящее время показателей, как SCORAD50, SCORAD75 и EASI50, EASI75, отражающих долю больных, у которых степень тяжести атопического дерматита в процессе лечения уменьшилась соответственно на 50% и более и на 75% и более
Summary
One of the methods of therapy for atopic dermatitis is long-wavelength ultraviolet therapy A (UVA-1therapy). For citation: Kubanov AA, Chikin VV, Karamova AE, Davletbaeva LK. Эффективность УФА-1-терапии больных атопическим дерматитом в различных дозах УФА-1-излучения вне зависимости от фототипа кожи в отсутствие сопутствующей терапии Table.
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