Abstract
During the 2016 Zika virus outbreak in Brazil, we detected Zika virus RNA in urine samples collected from Zika virus–positive pregnant women during different stages of pregnancy. Women had positive and negative intervals of viruria; 3 newborns had adverse outcomes. Further research is needed to clarify the relationship between viruria and outcomes for newborns.
Highlights
During the 2016 Zika virus outbreak in Brazil, we detected Zika virus RNA in urine samples collected from Zika virus– positive pregnant women during different stages of pregnancy
The Study During the February–October 2016 Zika virus outbreak, pregnant patients with Zika-like symptoms were treated at the Public Health Authority in São José do Rio Preto, Brazil
Pregnant women who were Zika virus positive by quantitative reverse transcription PCR (RT-qPCR) [6] were monitored by a multidisciplinary medical team at the Criança e Maternidade Teaching Hospital in São José do Rio Preto, and viruria levels in urine were measured until delivery
Summary
During the 2016 Zika virus outbreak in Brazil, we detected Zika virus RNA in urine samples collected from Zika virus– positive pregnant women during different stages of pregnancy. The Study During the February–October 2016 Zika virus outbreak, pregnant patients with Zika-like symptoms were treated at the Public Health Authority in São José do Rio Preto, Brazil. We collected serum and urine samples from these women during their first visit to the facility after symptom onset (Table) and tested their samples for Zika virus RNA [6].
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