Abstract
Cholangiocarcinoma, malignant tumor of epithelial cells of bile ducts has poor overall survival and prognosis. We report a case of non-resectable cholangiocarcinoma with a 57-month survival after incomplete R2 surgical margin resection of the tumor. A 52-year old man with generalized itching, jaundice, brownish urine, mild abdominal pain and weight loss of 8 kg in last two months presented. Imaging and surgical workups showed hilar cholangiocarcinoma (Klatskin tumor). Along with incomplete R2 margin resection we performed stent embedding and post-operative adjuvant chemotherapy. Based on current literature data there is no superiority of adjuvant chemotherapy after complete R0 resection compared to incomplete R2 resection. However, it seems that partial resection along with stent embedding and applied adjuvant chemotherapy in cases of locally advanced non-resectable cholangiocarcinoma may increase survival rate.
Highlights
Cholangiocarcinoma, malignant tumor of epithelial cells of bile ducts cover about 3% of all gastrointestinal tumors and 10-15% of all hepatobiliary tumors
In the presented case patient had a 57-month survival in spite of incomplete R2 surgical resection of the tumor. We present this case and investigate the “why” and “” of this long-term survival using a review on high level evidence literature
Patient became candidate for endoscopic retrograde cholangiopancreatography (ERCP) and received a stent that was embedded at the place of stenosis
Summary
Long-term survival of a patient with locally advanced hilar cholangiocarcinoma (Klatskin tumor): a case report and review on high level evidence.
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