Abstract
Fourteen patients who survived more than 5 years after disseminated ovarian carcinoma had been proved have been analyzed for factors that may have prolonged survival. Factors surveyed included treatment, histological grade and tumor type, age, marital status, and parity of patients. Chemotherapy appeared ineffective. Age, marital status, and parity were not considered significant. Surgery plus irradiation sometimes was effective, notably in the dysgerminoma. Low tumor grade significantly influenced survival in serous but not in endometrioid and mucinous carcinomas. In these, tumor type regardless of grade seemed more important. Intrinsic aspects of host-tumor relationships, possibly affecting growth activity, were implicated in the long survival times of patients with granulosa cell carcinoma, mesometanephroma, and the rare malignant mesothelioma. It is suggested that histologic types of ovarian carcinoma should be considered by graded and staged groups in the evaluation of therapeutic results.
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