Abstract
At the Heart Institute of Japan, Tokyo Women's Medical College, 474 aortic valve replacements (AVR) are performed using various kinds of prosthetic devices during the period of 1965, 5-1978, 12. Most popular valve prosthesis was Björk-Shiley valve totalling 215. 56 cases were subjected to study of more than 5 years follow up. They carried operative mortality of 16.1% and late mortality of 7.1%. Thromboembolism was 5.4%. 3 patients delivered 4 normal full term babies. There were 4 reoperations for aortic orifice with successful outcome. Cardiothoracic ratio, left ventricular strain pattern on ECG, blood pressure, pulmonary artery wedge pressure, cardiac indices, ejection fraction, end-diastolic volume have post-operatively returned almost to normal in majority of cases. Actuarial survival curve beyond 6 years after AVR was 98% up to 9 years.
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