LONG-TERM RESULTS OF MITRAL AND AORTIC VALVE REPLACEMENT WITH XENOPERICARDIAL PROSTHESIS «BIOLAB»

Abstract

Background Heart valve replacement with mechanical prostheses in elderly patients is associated with increased risk of bleeding due to the need of lifelong indirect anticoagulant therapy. Therefore, biological heart valve prosthesis is an option of choice. Aim To estimate long-term results of aortic and mitral valve replacement with xenopericardial prosthesis «BioLAB». Methods 150 stented biological prostheses «BioLAB» were implanted into the aortic and mitral position in the Department of Emergency Surgery for Acquired Heart Disease in the period from January 1993 to December 2008. 50 stentless biological prostheses «BioLAB» were implanted in the aortic position in the period from January 2008 to December 2012. Results 1-, 5- and 10-years survival in the recipients of stented xenopericardial prostheses «BioLAB» implanted in aortic position was 91.1±2.9%, 85.3±6.1% and 85.3±6.1%, respectively. 5-, 10- and 15-years survival among those who received mitral valve replacement was 72.31%±5.56%, 55.18%±6.61%, and 22.77%±12.13%, respectively. There were no cases of redo surgeries for valve tissue degeneration among the recipients of stented and stentless aortic valve prostheses within the follow-up. 10-, 12- and 15-years freedom from mitral valve degeneration was 61.08±7.32%, 50.21±9.56%, and 43.6±10.65%. Conclusion Stented xenopericardial bioprostheses «BioLAB» implanted in the aortic position provide good and encouraging hemodynamic results in the long-term period time. There were no signs of tissue degeneration of the stented heart valves within the 10-years follow-up. Similar results were obtained for the stentless bioprosthesis within the 7-years follow-up. The period of 8.5 years after mitral valve replacement with «BioLAB» is critical for tissue degeneration of bioprosthesis.