Abstract
Long-term results of 182 patients undergoing multiple valve replacement with a mechanical valve in the aortic position and a biological valve in the mitral and tricuspid position from Jan. 1977 to Jan. 1989 were retrospectively analysed. It is concluded that, excepting patients who need triple or double valve replacement, who are over 61 years old, and who are classified into New York Heart Association functional class 4, a mechanical valve in the mitral position is the first-choice procedure leading to better long-term consequence. However, an antiplatelet drug added to warfarin is recommended for postoperative anticoagulant therapy, if multiple valve replacement is performed only with using mechanical valves. We continue actively to use to biological valve in the tricuspid position in cases associating with severe tricuspid regurgitation, because excellent long-term results can be attained by the replacement.
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