Long‐term remission of severe livedoid vasculopathy treated with a short course of intravenous immunoglobulin

Abstract

We present a case of acute flare of severe livedoid vasculitis (LV) which had been refractory to a combination of immunosuppressive and anti-thrombotic agents, but remitted for 7 years after only two cycles of intravenous immunoglobulin (IVIV). This suggests that IVIG may exert unique immunological and/or anti-thrombotic actions different from other agents, and that only short-term or on-demand use of IVIG for acute flare of LV may dampen down disease activity and induce a prolonged remission of LV.