Abstract
The study of long-term relapses that present 8 years or more after mastectomy in breast cancer patients indicates these cases are strictly related to the presence of hormone receptors and particularly to estrogen receptors. It is possible to infer that the presence of estrogen receptors indirectly conditions the formation of antimitotic factors more effective than those used for therapy, to the point of determining in some cases the phenomenon of long-term relapses.
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