Long term reduction in vascular morbidity and mortality in men with severe OSA

Abstract

▴ Marin JM, Carrizo SJ, Vicente E, Agusti AGN. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet2005;365:1046–53 [OpenUrl][1][PubMed][2][Web of Science][3] Evidence from observational studies has implicated obstructive sleep apnoea (OSA) as a risk factor for cardiovascular and cerebrovascular mortality. However, such studies have been complicated by the presence of uncontrolled co-factors such as obesity, smoking, and diabetes mellitus and by the absence of randomisation. There has been little … [1]: {openurl}?query=rft.jtitle%253DLancet%26rft.stitle%253DLancet%26rft.aulast%253DMarin%26rft.auinit1%253DJ.%2BM.%26rft.volume%253D365%26rft.issue%253D9464%26rft.spage%253D1046%26rft.epage%253D1053%26rft.atitle%253DLong-term%2Bcardiovascular%2Boutcomes%2Bin%2Bmen%2Bwith%2Bobstructive%2Bsleep%2Bapnoea-hypopnoea%2Bwith%2Bor%2Bwithout%2Btreatment%2Bwith%2Bcontinuous%2Bpositive%2Bairway%2Bpressure%253A%2Ban%2Bobservational%2Bstudy.%26rft_id%253Dinfo%253Apmid%252F15781100%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=15781100&link_type=MED&atom=%2Fthoraxjnl%2F60%2F6%2F503.atom [3]: /lookup/external-ref?access_num=000227731800029&link_type=ISI