Abstract
Primary gliosarcoma (PGS) is rare and is known for extra cranial metastases. The overall outcome is dismal and hence the focus is on providing the best quality of life. This report describes a seventy-year-old lady who at presentation had metastatic primary gliosarcoma with intractable cough. Her lung lesion was treated with stereotactic body radiotherapy (SBRT) to a dose of 10 Gy per fraction for three consecutive days. She was free of cough till her death at eighteen months after treatment. This is probably the first reported case of excellent long-term quality of life in a patient of metastatic primary gliosarcoma.
Highlights
Gliosarcoma (GS) constitutes 1.8-2.8% of all radiotherapy (SBRT) delivers high dose in short time glioblastoma multiforme (GBM).[1]
positron emission tomography (PET) scan done six months later showed reduction in lung lesion size, the soft tissue lesions had increased in size but patient still remained asymptomatic
Different phases of breathing cycle are captured onto the computer with the help of fibre optic cables and light emitting diode’s (LED) on the jacket that patient wears during treatment
Summary
Gliosarcoma (GS) constitutes 1.8-2.8% of all radiotherapy (SBRT) delivers high dose in short time glioblastoma multiforme (GBM).[1] It can be primary with minimal toxicity. This is an attempt to present a when it occurs “de novo” as opposed to secondary when case report of a metastatic primary gliosarcoma who initially the patient was treated as glioma and had complete relief from cough until her death. The treatment is same as that of GBM which includes maximum safe resection followed by adjuvant radiation and temozolamide.[5]
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