Abstract
BackgroundThe objective of this study was to evaluate the overall outcomes and complications of transvaginal mesh (TVM) placement for the management of pelvic organ prolapse (POP) with different meshes with a greater than 10-years of follow-up.MethodsWe performed a retrospective review of patients with POP who underwent prolapse repair surgery with placement of transvaginal mesh (Prolift kit or self-cut Gynemesh) between January 2005 and December 2010. Baseline of patient characteristics were collected from the patients’ medical records. During follow-up, the anatomical outcomes were evaluated using the POP Quantification system, and the Patient Global Impression of Improvement (PGI-I) was used to assess the response of a condition to therapy. Overall postoperative satisfaction was assessed by the following question: “What is your overall postoperative satisfaction, on a scale from 0 to 10?”. Relapse-free survival was analyzed using Kaplan–Meier curves.ResultsIn total, 134 patients were included. With a median 12-year (range 10–15) follow-up, 52 patients (38.8%) underwent TVM surgery with Prolift, and Gynemesh was used 82 (61.2%). 91% patients felt that POP symptom improved based on the PGI-I scores, and most satisfied after operation. The recurrence rates of anterior, apical and posterior compartment prolapse were 5.2%, 5.2%, and 2.2%, respectively. No significant differences in POP recurrence, mesh-associated complications and urinary incontinence were noted between TVM surgery with Prolift versus Gynemesh.ConclusionsTreatment of POP by TVM surgery exhibited long-term effectiveness with acceptable morbidity. The outcomes of the mesh kit were the same as those for self-cutmesh.
Highlights
The objective of this study was to evaluate the overall outcomes and complications of transvaginal mesh (TVM) placement for the management of pelvic organ prolapse (POP) with different meshes with a greater than 10-years of follow-up
Since gynecologists began using mesh for surgical treatment of stress urinary incontinence (SUI) as well as transvaginal repair of pelvic organ prolapse (POP) in the mid-1990s [1], some randomized controlled trials have reported the effectiveness of mesh surgery compared
Previous publications reported that the long-term outcomes of surgical treatment of POP with mesh offered low recurrence rates, better satisfaction, and high cumulative reoperation and mesh exposure rates [6,7,8]
Summary
The objective of this study was to evaluate the overall outcomes and complications of transvaginal mesh (TVM) placement for the management of pelvic organ prolapse (POP) with different meshes with a greater than 10-years of follow-up. Since gynecologists began using mesh for surgical treatment of stress urinary incontinence (SUI) as well as transvaginal repair of pelvic organ prolapse (POP) in the mid-1990s [1], some randomized controlled trials have reported the effectiveness of mesh surgery compared. We aimed to evaluate the outcomes following synthetic mesh placement by the vaginal route for POP with greater than 10 years of follow-up in a larger group, and to compare the outcomes of pelvic floor repair with different meshes
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