Long-term outcome of patients with biliary pancreatitis not undergoing cholecystectomy: a retrospective study

Abstract

Background and objective Most acute pancreatitis are of biliary origin and undergoing a cholecystectomy is recommended to prevent recurrence. However, some patients will never be referred to surgery. We reviewed the long-term follow-up of these group of patients Methods All cases of biliary pancreatitis presented from January 2015 to December 2017 that did not receive a cholecystectomy were analyzed. Epidemiologic data and Charlson comorbidity Index (CCI) were recorded. Recurrent episodes of pancreatitis or biliary events and mortality during the follow-up period was recorded. Results A total of 104 patients were included in the study (30.4% of all biliary pancreatitis). Median age was 82 years (range 27-96). Average CCI was 5 (range 0-18). The median follow-up period was 37 months (range 1-70). A total of 41 patients (39.4%) had gallstone-related complications. Twenty-three patients (22,1%) had recurrent pancreatitis and 34 (32,7%) developed biliary events. Decease occurred in 25 patients during follow-up (24%) but only 6 (5,8%) were due to gallstone-related complications. Non-related mortality was 15.5% in patients who refused surgery and 25% if high comorbidity patients. Conclusion Patients that are not cholecystectomized are at high risk for biliary event and pancreatitis recurrence. Conservative treatment and surgical abstention should be individualized and reserved to high comorbid patients with short life expectancy.