Abstract
An improved method using the principle of internal calorimetry as an automatic recorder is described for long term studies measuring liver blood flow in 28 rats. The daily measurements of liver blood flow under physiological conditions showed very constant values with a low standard deviation. One problem encountered was the development of connective tissue around the thermocouple in three rats. Methods to avoid this complication are discussed. This method seems to be appropriate to study liver blood flow in the rat in long term physiological or pharmacological studies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have