Abstract
In three different in-vivo studies the formation of reactive oxygen species (ROS) was investigated utilizing the blood of healthy women who use hormonal contraception (HC) and a control group of non-HC users. ROS were quantified by a validated, commercially available photometric kit. In the first study ROS were measured in blood of women from various regions of the Austrian territory. The findings revealed that women using HC had significantly higher ROS levels in the blood (mean 572 + 136 FORT; one FORT unit represents 0,26 mg hydrogen peroxide per litre) than the non-HC group, HC (347 + 80 FORT). In the second study, ROS from female students of pharmacy were measured. The results were similar to the first investigation: 519 + 92 FORT in the group using HC and 331 + 68 FORT in the controlled non-HC group. These outcomes are statistically significant (p
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