Abstract
The influence of long-term treatment with parathyroid hormone (PTH) on blood pressure (BP) development in stroke prone spontaneously hypertensive rats (SHR/SP) was investigated. Acute i.v. administration of PTH decreased BP dose dependently. Long-term treatment of SHR/SP with 300 IU PTH s.c. per day clearly attenuated the BP increase. Treatment with PTH was associated with marked hypercalcemia, increased urinary excretion of calcium and cAMP.
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Schedule a callMore From: European Journal of Pharmacology: Molecular Pharmacology
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