Abstract
Purpose: This study aimed to nd the risk factors associated with the development of brosis in follow-up CT in patients of COVID-19 pneumonia. In this retrospective study, fty-four patients with RT-Methods: PCR proved COVID-19 pneumonia with two chest CTs in a 12-month interval between the initial and follow-up CT were included. Patients were classied into two groups: Patients with complete resolution and patients with brosis on follow-up CT. Demographic, laboratory, and therapeutic data and CT ndings were compared and analyzed. A total of 54 patientsResults: (38 men, 16 women) were included in this study. Post-COVID brosis and brotic-like changes were observed on follow-up CT scans in 34 of the 54 patients (63%). The remaining 20 patients (37%) showed no brotic changes with complete resolution. Patients with post covid brosis were signicantly older than those with normal CT. Males were affected more than females. Patients with post covid brosis had more comorbidities when compared with patients without comorbidities. Post-Covid brosis patients had a greater frequency of ICU admission, high frequency noninvasive mechanical ventilation( NIV), higher peak levels of C-reactive protein and D-dimer levels, low level of SpO2, and high CT Severity score in initial CT. Conclusion: Elderly patients, patients with comorbidities, high CT severity score, longer duration of hospital stay, ICU admission, high CRP and D dimer levels, Patients with NIV were associated with more prevalence of brosis in follow up CT.
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