Long-term follow-up of a non-randomised prospective cohort of one hundred and ninety two total knee arthroplasties using the NexGen implant.

Abstract

The purpose of this study was to retrospectively analyse the clinical, functional and radiological outcomes, and the long-term survivorship of the NexGen Legacy Posterior Stabilised (LPS) knee prosthesis (Zimmer Biomet, Warsaw, IN, USA). Between 1996 and 2001, 197 primary NexGen LPS total knee arthroplasties (TKAs) were implanted by a single surgeon; 132 prostheses in 124 patients with a minimum follow-up of 15years were included in the study. Surgical procedure and post-operative care were the same for all patients. All patients were assessed through the International Knee Society (IKS) scores and range of motion (ROM). A complete radiological study was performed for all patients. Failure was defined as revision of at least one prosthetic component for any cause. IKS knee and function scores, as well as ROM and leg alignment, significantly improved at the latest follow-up (p ≤ 0.05). No significant differences were found between fixed- and mobile-bearing groups. Seven implant failures were reported; the implant survival rate (overall) was 94.7% at the latest follow-up. This study showed optimal survivorship of the NexGen LPS, associated with a significant improvement in overall outcomes at a minimum follow-up of 15years.